The effects of myofascial induction therapy in survivors of head and neck cancer: a randomized, controlled clinical trial.
Featured on Physle Daily · Tuesday, 21 July 2026
Researchers in this trial tested whether myofascial induction therapy, a hands-on manual therapy technique, could help people who had survived head and neck cancer and were living with lingering physical effects. They recruited 46 survivors, gave 20 of them 18 sessions of this therapy over 6 weeks, and compared them to 23 others who received standard care and waited. The therapy group showed improvements in several areas: they could open their mouth wider, had less temporomandibular dysfunction (jaw joint problems), had better neck endurance and range of motion, and showed some gains in shoulder movement and flexibility. However, the improvements were mixed.
While some changes were statistically significant, only the gains in neck movement and affected shoulder abduction appeared clinically meaningful, meaning large enough that someone might actually notice the difference in daily life. Muscle strength and how people felt about their overall physical fitness didn't improve. The authors noted the study was small and lasted only 6 weeks, so they called for longer follow-up studies and larger sample sizes before drawing firm conclusions.
This study looked at whether a hands-on therapy technique called myofascial induction therapy could help with some of the physical problems that linger after head and neck cancer treatment. About 40 people received this therapy, which involved 18 sessions over 6 weeks, while another group received their usual care. People who had the therapy did notice some real improvements.
They were able to open their mouth wider, had less jaw joint pain and stiffness, and found it easier to move their neck and certain parts of their shoulders. Some of these gains felt meaningful in their day-to-day life, especially moving their neck and one shoulder movement. That said, the therapy didn't help with everything.
There wasn't any change in overall hand grip strength or how people felt about their general fitness level. The study was fairly small and only lasted 6 weeks, so we don't yet know how long these improvements last or whether they would continue if people kept going with the therapy.
This is a summary of research, not medical advice. Talk to your own healthcare provider about anything affecting your care.
This small RCT adds some evidence for myofascial induction therapy in a population where treatment options are limited and sequelae are often multifaceted. The intervention produced statistically significant improvements across several domains: mouth opening, temporomandibular dysfunction, cervical endurance, cervical AROM, and selective shoulder movements.
The clinical meaningfulness signal appears strongest for cervical AROM and affected shoulder abduction, which aligns with what we might expect from a neck and shoulder focused manual therapy approach. The findings are mixed enough to warrant caution. No improvements appeared in unaffected shoulder movements, grip strength, or self-reported physical fitness, suggesting the therapy's reach may be more focal than broad.
The sample was modest (20 in the intervention group), the follow-up period was short (6 weeks), and there was no sham or active control group, only a waitlist comparison. The authors appropriately acknowledge these limitations and call for larger, longer-duration studies and consideration of multimodal approaches.
For now, this represents preliminary support for a technique that may address specific regional restrictions in this population, but much remains to be established about magnitude of effect, durability, and how MIT combines with other interventions.
A 6-week myofascial induction therapy protocol (18 sessions over alternate days) produced statistically significant improvements in mouth opening, temporomandibular dysfunction, cervical endurance, cervical range of motion, and some shoulder movements, but only cervical range of motion and affected shoulder abduction were clinically meaningful.
No statistically significant improvements were observed in unaffected shoulder movements, handgrip strength, or perceived physical fitness after the 6-week protocol.
The study included 46 survivors (20 in the intervention group, 23 in the waitlist control) and the authors identified the need for longer follow-up designs, larger sample sizes, and investigation of multimodal treatments.
Source
Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer
Ortiz-Comino L, Martín-Martín L, Galiano-Castillo N et al. · 2022
doi: 10.1007/s00520-022-07482-9