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Manual Therapy Systematic review and meta-analysis

The effects of myofascial release technique for patients with low back pain: A systematic review and meta-analysis.

Myofascial release is a manual therapy technique often used alongside other treatments for low back pain, but how much it actually adds has been unclear. This systematic review and meta-analysis pooled data from eight randomized controlled trials, involving 386 patients total, comparing myofascial release against control interventions for pain, back disability, lumbar range of motion, and quality of life. The pooled results showed a statistically significant reduction in back disability when myofascial release was used, but no statistically significant differences were found for pain intensity, quality of life, or lumbar range of motion in any direction tested. This mixed pattern, one positive outcome among several null ones, is worth noting because it suggests any benefit may be narrow rather than broad.

The evidence base remains limited in size, with considerable inconsistency between trials for several outcomes, so these findings should be read as preliminary rather than conclusive.

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This is a summary of research, not medical advice. Talk to your own healthcare provider about anything affecting your care.

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Source

Complementary therapies in medicine

Chen Z, Wu J, Wang X et al. · 2021

doi: 10.1016/j.ctim.2021.102737

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Previously in Manual Therapy
2026-08-18Comparison of dry needling and trigger point manual therapy in patients with neck and upper back myofascial pain syndrome: a systematic review and meta-analysis.2026-08-17Experiences and perceptions of Chinese patients enrolled in a clinical trial assessing tuina and manual therapies for knee osteoarthritis: a nested qualitative study.2026-08-16Effects of midfoot joint mobilization on ankle-foot morphology and function following acute ankle sprain. A crossover clinical trial. Browse the full Manual Therapy archive →
A note on accuracy

Summaries are AI-generated from each paper's abstract and are for learning, not clinical decision-making. They may miss nuance or occasionally misstate details from the source, so always read the original paper before applying findings in practice. Nothing on this site is medical advice.