Is connective tissue massage effective in individuals with fibromyalgia?
Featured on Physle Daily · Saturday, 5 September 2026
Fibromyalgia causes widespread pain and fatigue that can be hard to manage, and clinicians often look for manual therapies to add alongside exercise. This small trial compared clinical Pilates exercises alone against the same Pilates program combined with connective tissue massage, a technique applied to skin and underlying tissue, in 32 women over six weeks. Both groups improved on several measures, including disease impact and mental and physical quality of life, but when the researchers compared how much each group changed, the only outcome group differed by after treatment was the number of painful body regions, which improved more in the massage-plus-Pilates group.
Other outcomes, such as anxiety and functional status, did not show a clear advantage of adding massage over Pilates alone. Because the trial was small, with only 15 and 17 women per group, and outcomes were only measured immediately after the intervention, these findings should be seen as preliminary rather than conclusive evidence that connective tissue massage adds meaningful benefit.
If you live with fibromyalgia, you know how frustrating it can be to find treatments that actually help with widespread pain and fatigue. This study looked at whether adding a hands-on technique called connective tissue massage to a Pilates exercise program made a difference compared to doing Pilates exercises alone, in a small group of 32 women followed for six weeks. Both groups saw improvements in several areas, including how much fibromyalgia affected daily life and both physical and mental quality of life.
When researchers compared the actual amount of change between the two groups, the only clear difference was in the number of painful body areas, which improved more in the group that received both massage and exercise. There wasn't a clear extra benefit from massage for anxiety or daily function measures. Because this trial included so few participants and only looked at short-term results, it's a starting point rather than firm proof that adding this massage technique improves fibromyalgia symptoms more broadly.
This is a summary of research, not medical advice. Talk to your own healthcare provider about anything affecting your care.
This randomised controlled trial compared clinical Pilates exercises alone (n=17) against clinical Pilates combined with connective tissue massage (n=15) in women with fibromyalgia, over six weeks of treatment delivered three times weekly. Within-group improvements were seen in both arms for the Fibromyalgia Impact Questionnaire and SF-36 physical and mental component scores, and the intervention group additionally showed within-group improvement in the Pain Location Inventory, while the control group showed a within-group improvement in anxiety scores measured by the Beck Anxiety Inventory. Critically, when delta (pre-post change) values were compared between groups, the only statistically significant between-group difference was in the Pain Location Inventory (p=0.023), favouring the combined intervention group, with a reported large effect size.
No between-group differences were detected for disease impact, functional status, anxiety, or quality of life measures, meaning the within-group gains in those domains cannot be attributed specifically to the addition of massage. With only 32 participants total and no long-term follow-up reported, this trial offers preliminary rather than definitive evidence, and the abstract does not address blinding, adverse events, or maintenance of effects beyond the immediate post-treatment assessment.
In this small trial of 32 women with fibromyalgia, adding connective tissue massage to clinical Pilates was associated with a statistically significant between-group reduction in the number of painful body regions compared to Pilates alone.
Both treatment groups showed within-group improvements in disease impact and physical and mental quality of life scores, but these improvements did not differ significantly between groups after treatment.
With only 15 to 17 participants per group and no long-term follow-up reported, these findings are preliminary and require confirmation in larger trials before conclusions can be drawn about the added value of connective tissue massage.
Source
Journal of bodywork and movement therapies
Basakci Calik B, Gur Kabul E, Keskin A et al. · 2024
doi: 10.1016/j.jbmt.2023.09.006