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Manual Therapy Systematic review and meta-analysis

Effects of cupping therapy on chronic musculoskeletal pain and collateral problems: a systematic review and meta-analysis.

Chronic musculoskeletal pain is common and often frustrating to treat, and cupping therapy, where suction cups are applied to the skin, is one of the complementary approaches people turn to. This review pooled randomised controlled trials comparing cupping against other treatments or no treatment for people with chronic musculoskeletal pain, looking at pain intensity, physical function, and mental health. The pooled results showed a significant reduction in pain intensity with cupping, though the effect size varied a great deal between the included trials.

However, cupping showed no significant improvement in functional disability or mental health outcomes. This split result is worth paying attention to: an intervention can ease reported pain without translating into better daily function or mood. The main limitation is substantial inconsistency across studies, meaning the true size of the pain benefit is uncertain even though the overall direction favoured cupping.

If you live with ongoing muscle or joint pain, you may have wondered whether cupping therapy, where cups are placed on the skin to create suction, actually helps. This review combined results from multiple randomised trials testing cupping against other treatments or no treatment.

The overall finding was that cupping seemed to reduce how intense people's pain felt. That's a meaningful signal, but it came with a big asterisk: results varied a lot from study to study, so how much relief any one person might expect isn't very predictable from this evidence. Just as important, cupping did not show a significant improvement in physical function, meaning people's ability to move and do daily activities did not clearly get better.

It also did not show a significant improvement in mental health measures like mood or emotional wellbeing. So while pain ratings may drop, this doesn't necessarily mean people become more functional or feel psychologically better.

This is a case where feeling less pain and functioning better are not the same thing, and the current evidence only supports the first.

This is a summary of research, not medical advice. Talk to your own healthcare provider about anything affecting your care.

This systematic review and meta-analysis pooled randomised controlled trials evaluating cupping therapy for chronic musculoskeletal pain, assessing pain intensity, functional disability, and mental health outcomes, with searches through December 2024 across five databases and risk of bias assessed via Cochrane and Evidence Project tools. The pooled random-effects estimate for pain intensity was a standardised mean difference of -1.17 (95% CI -1.93 to -0.42, p=0.002), rated as moderate quality by GRADE, but heterogeneity was very high (I²=94%), meaning individual trial results diverged substantially and the summary effect should be interpreted with caution regarding its precise magnitude. For functional disability, the pooled effect was not statistically significant (SMD -0.24, 95% CI -0.93 to 0.46, p=0.51, I²=93%), and for mental health outcomes there was also no significant effect (SMD 0.08, 95% CI -0.12 to 0.27, p=0.46, I²=0%), the latter with notably low heterogeneity suggesting more consistent null findings across trials.

Overall, this body of evidence supports an immediate analgesic signal for cupping but does not establish improvements in function or psychological wellbeing, and the marked inconsistency in the pain outcome limits confidence in translating the pooled estimate to individual clinical expectations.

1

Pooled analysis of randomised trials found a statistically significant reduction in pain intensity with cupping therapy (SMD -1.17), rated moderate quality evidence.

2

Cupping showed no statistically significant improvement in functional disability or mental health outcomes across the pooled trials.

3

Heterogeneity across studies was very high for the pain intensity outcome (I²=94%), meaning the pooled effect size should be interpreted with caution.

Source

BMJ open

Jia Y, Dong X, Chai Y et al. · 2025

doi: 10.1136/bmjopen-2024-087340

Read paper →
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A note on accuracy

Summaries are AI-generated from each paper's abstract and are for learning, not clinical decision-making. They may miss nuance or occasionally misstate details from the source, so always read the original paper before applying findings in practice. Nothing on this site is medical advice.