Physle Daily
Manual Therapy Pilot randomised controlled trial

Combining specific task-oriented training with manual therapy to improve balance and mobility in patients after stroke: a mixed methods pilot randomised controlled trial.

After a stroke, balance and mobility problems often persist for years, and clinicians keep looking for ways to combine hands-on techniques with functional retraining. This pilot trial asked whether adding manual therapy to the ankle joint, alongside task-oriented training focused on real-life movements, might help chronic stroke patients more than task-oriented training alone or no intervention at all, and whether such a study could even be run properly. Thirty-six people were split across the three groups, with supervised sessions twice weekly plus home practice over four weeks. The pilot confirmed the design was workable in terms of recruiting, retaining and engaging participants, and patients described the training as acceptable.

Both active approaches showed preliminary improvements in balance, walking speed, mobility and ankle range of motion, plus some quality of life measures, but this was a small feasibility study, not a definitive test of effectiveness, so these results need confirming in a larger trial.

If you're living with the effects of a stroke, you may know how much balance and walking difficulties can affect daily life. Researchers wanted to see if adding a specific hands-on ankle treatment to task-focused exercise training, built around real everyday movements, could help more than the exercise training alone, or no treatment. Thirty-six people took part, split into three groups, doing supervised sessions twice a week and home exercises on their own for four weeks.

The main goal of this study was to check whether a bigger trial would even be practical, and the answer was yes, people stuck with it and found the training acceptable. On top of that, both groups doing active training showed encouraging early signs of improvement in balance, walking speed, ankle flexibility, and some quality of life measures. However, this was a small pilot study designed mainly to test feasibility, not to prove the treatment works.

The improvements seen are preliminary and need to be confirmed by a larger, more rigorous trial before anyone can be confident about how much they truly help.

This is a summary of research, not medical advice. Talk to your own healthcare provider about anything affecting your care.

This assessor-blinded pilot randomised controlled trial (n=36) compared talocrural manual therapy combined with task-oriented training (MT-TOT), task-oriented training alone (TOT), and a no-intervention control in chronic stroke patients, primarily to establish feasibility for a full-scale trial. Recruitment, retention, adherence, adverse events, falls and acceptability were assessed, and the pilot criteria were met, with qualitative interviews indicating high acceptability consistent with the Theoretical Framework of Acceptability. Secondary, exploratory efficacy analyses reported effect sizes for balance (0.714), walking speed (0.683), general mobility (0.265), dual-task mobility (0.595), falls (0.037), active and passive talocrural dorsiflexion range of motion (0.603 and 0.751), and health-related quality of life domains related to activity and participation (0.332 to 0.784), favouring the active intervention groups.

These figures should be interpreted cautiously given the small sample size, pilot design, and lack of power for definitive between-group comparisons. The abstract does not report a direct statistical comparison establishing MT-TOT as superior to TOT alone, so whether adding manual therapy provides additional benefit beyond task-oriented training remains unresolved. A larger, adequately powered trial is needed to confirm these preliminary efficacy signals.

1

The pilot trial met its feasibility goals, with acceptable recruitment, retention, adherence and patient acceptability of task-oriented training with and without ankle manual therapy.

2

Preliminary, exploratory analyses in this small trial of 36 patients suggested improvements in balance, walking speed, mobility, ankle range of motion and some quality of life domains after task-oriented training, with or without manual therapy.

3

Because this was a small pilot study without a direct statistical comparison of the two active groups reported, whether adding manual therapy improved outcomes beyond task-oriented training alone remains unclear.

Source

Disability and rehabilitation

Traxler K, Baum E, Klotz E et al. · 2024

doi: 10.1080/09638288.2023.2193432

Read paper →
Previously in Manual Therapy
2026-09-12Hypoalgesic effects of specific vs non-specific cervical manipulation in healthy subjects: a randomized crossover trial.2026-09-11The Effect of Adding Dry Needling to Physical Therapy in the Treatment of Cervicogenic Headache: A Randomized Controlled Trial.2026-09-10Comparison of the efficacy of manual treatment according to fascial distortion model versus joint mobilization in patients with shoulder impingement: A randomized clinical trial. Browse the full Manual Therapy archive →
A note on accuracy

Summaries are AI-generated from each paper's abstract and are for learning, not clinical decision-making. They may miss nuance or occasionally misstate details from the source, so always read the original paper before applying findings in practice. Nothing on this site is medical advice.