Immediate effects of Mulligan's techniques on pain and functional mobility in individuals with knee osteoarthritis: A randomized control trial.
Featured on Physle Daily · Sunday, 27 September 2026
For people with knee osteoarthritis, manual therapy techniques like Mulligan's mobilization with movement are sometimes used alongside other treatments, but it has been unclear how much the technique itself contributes versus simply receiving hands-on attention. This small randomized trial compared a single session of Mulligan's mobilization against a sham version, where the therapist mimicked the hand placement without applying the actual gliding force, in thirty adults with knee osteoarthritis, measuring pain and a timed mobility test immediately afterward. The group receiving the real technique reported lower pain and moved faster on the mobility test than the sham group after the session. Interestingly, the sham group also reported less pain, though their mobility scores did not change, suggesting something about the hands-on contact itself may influence pain perception.
Because this was a single immediate-effect session in a small sample, it cannot show whether these benefits last or how they compare to broader treatment programs.
If you have knee osteoarthritis, you may have heard about manual therapy techniques where a physiotherapist moves your knee in a specific way while you move it too, sometimes called Mulligan mobilization. This study looked at whether that specific technique makes a real difference, compared with a similar-feeling touch that didn't include the actual movement technique. Thirty people took part, split into two groups.
One group received the genuine technique, and the other received a sham version where the therapist's hands were placed the same way but without the actual gliding motion. Right after the session, people who received the real technique reported less pain and completed a timed walking and standing test faster than those in the sham group.
Interestingly, the sham group also felt less pain afterward, even though their movement speed didn't improve, hinting that touch and attention alone may partly explain pain relief. This was a small study looking only at immediate effects from a single session, so it doesn't tell us whether these benefits would last over time or how they'd fit into a longer treatment plan.
This is a summary of research, not medical advice. Talk to your own healthcare provider about anything affecting your care.
This trial addresses a specific question in manual therapy for knee osteoarthritis: when Mulligan's mobilization with movement is used on its own, does it produce effects beyond nonspecific contact, given that it is usually studied only as part of multimodal programs? Thirty participants were randomized to receive either genuine Mulligan glides or a sham mobilization mimicking hand placement without the gliding force, with a blinded assessor recording pain (numerical pain rating scale) and functional mobility (timed up and go) immediately pre- and post-intervention. The intervention group showed significantly lower post-intervention pain and faster timed up and go scores than the sham group, and within-group improvements from baseline were significant for both outcomes in the intervention arm. Notably, the sham group also showed a significant within-group reduction in pain, though not in mobility, raising the possibility that therapist contact or expectation contributes to pain outcomes even without the specific gliding technique. The main limitation is that this captures only immediate, single-session effects in a small sample of thirty participants, so it cannot speak to durability of benefit, cumulative dosing effects, or how this isolated technique performs within typical multimodal care.
The sham pain finding also means specificity of the mechanism, rather than nonspecific contact effects, remains unresolved.
In this small trial of thirty participants, Mulligan's mobilization produced significantly greater immediate pain relief and faster timed up and go performance than sham mobilization.
Within the sham group, pain scores also improved significantly after the mock intervention, though timed up and go performance did not change, suggesting a possible nonspecific contact or expectation effect on pain.
Findings are based on a single immediate-effect session in a small sample, so they do not establish whether benefits persist over time or how the isolated technique compares within broader treatment programs.
Source
Physiotherapy research international : the journal for researchers and clinicians in physical therapy
Bhagat M, Neelapala YVR, Gangavelli R · 2020
doi: 10.1002/pri.1812