Immediate effects of a lumbar spine manipulation on pain sensitivity and postural control in individuals with nonspecific low back pain: a randomized controlled trial.
Featured on Physle Daily · Friday, 30 October 2026
Spinal manipulation is often used for low back pain with the idea that it reduces pain and improves how the body controls posture and balance. This trial compared a real high-velocity low-amplitude lumbar manipulation against a simulated version in 24 people with nonspecific low back pain, measuring pain and several postural control measures before and after a single session. Both groups reported less pain afterward, with no statistically significant difference between real and simulated manipulation, suggesting the drop in reported pain intensity may not be specific to the manipulation itself. A more objective pain measure, pressure pain threshold, showed no significant change.
Among postural control outcomes, only one measure (sway ellipse area) differed between groups, favoring the control group, an isolated finding that could reflect chance. The main limitation is the very small sample from a single session, which limits confidence in any conclusions about manipulation's immediate effects.
If you've had manipulation (a quick, forceful adjustment) done to your lower back for pain, you might wonder whether it specifically eases pain or just feels like it helps because of the experience itself. This small study of 24 people compared a real manipulation to a fake, simulated version in a single session, checking pain levels and balance-related measures before and after. Both groups said their pain felt better right after, whether they got the real manipulation or the sham one, meaning the improvement couldn't be clearly tied to the manipulation itself.
A pressure-based pain test, which is less influenced by expectation, didn't show a clear change either. For balance, there was little to suggest that manipulation changed how people controlled their posture.
Because this was a small, single-session study, these findings are an early, limited look rather than a clear answer, and they don't tell us about manipulation's effects over longer treatment courses.
This is a summary of research, not medical advice. Talk to your own healthcare provider about anything affecting your care.
This trial speaks to a question clinicians often face: does a single lumbar high-velocity low-amplitude manipulation produce measurable immediate effects on pain sensitivity and postural control beyond what a simulated manipulation achieves? In this participant- and assessor-blinded randomized controlled trial of 24 people with nonspecific low back pain, self-reported pain intensity dropped significantly over time in the pooled sample, but the group-by-time interaction was not significant, meaning the abstract does not establish that the real manipulation outperformed the sham procedure on subjective pain. Pressure pain threshold, a more objective proxy for pain sensitivity, showed no significant effect in either group, which tempers claims that manipulation produces a measurable hypoalgesic effect beyond expectation. Among postural control variables (ellipse area, center of pressure excursion, center of pressure root-mean-square velocity, and differences between center of pressure and projected center of gravity), only ellipse area differed significantly between groups, favoring the control condition, an isolated result among several outcomes that could represent a chance finding rather than a genuine postural effect.
The small sample size and single-session design limit how far these findings can generalize to clinical practice or to cumulative treatment effects, and the abstract does not report on adverse events.
In this small trial of 24 participants, both the real spinal manipulation group and the simulated (placebo) manipulation group reported less pain immediately afterward, with no statistically significant difference reported between groups.
No significant effect of the manipulation was found for pressure pain threshold, a more objective measure of pain sensitivity.
For postural control, only the postural sway ellipse area showed a significant group difference (greater in the control group), while no other postural control measures showed an effect of manipulation.
Source
Chiropractic & manual therapies
Fagundes Loss J, de Souza da Silva L, Ferreira Miranda I et al. · 2020
doi: 10.1186/s12998-020-00316-7