Effects of Manual Therapy on Parkinson's Gait: A Systematic Review.
Featured on Physle Daily · Tuesday, 3 November 2026
People with Parkinson's disease often develop gait problems, and manual therapy, which includes hands-on techniques like joint mobilization or soft tissue work, is sometimes used alongside standard rehabilitation. This review asked whether manual therapy actually helps walking in Parkinson's disease by pooling results from controlled trials that compared it with other approaches. Only three trials met the criteria. One outcome, a walking balance and adaptability measure called the Dynamic Gait Index, showed improvement with manual therimony that was rated as moderate-quality evidence.
Other measures like stride length and arm swing velocity also improved in one small, lower-quality trial, while range of motion during walking showed no significant difference between groups. The main limitation is the very small number of trials, meaning the overall evidence is not strong, and the authors call for more randomized trials before any firm conclusions can be drawn.
If you or someone you know has Parkinson's disease, you may have heard about manual therapy, hands-on treatments like joint and soft tissue work, being used alongside physiotherapy to help with walking. This review looked at what the research actually shows about whether that approach helps. The researchers could only find three controlled studies on this topic, which is a small amount of evidence to draw conclusions from.
One walking test showed improvement with manual therapy that was backed by moderate-quality evidence, and some specific measures like stride length and arm swing speed also seemed to improve in one smaller, weaker study. However, measures of joint flexibility during walking did not differ significantly between groups. Overall, the researchers concluded there isn't strong evidence yet to say manual therapy reliably improves walking in Parkinson's disease.
More well-designed studies are needed before anyone can say with confidence how much it helps.
This is a summary of research, not medical advice. Talk to your own healthcare provider about anything affecting your care.
For clinicians weighing whether manual therapy has a role in addressing gait impairment in Parkinson's disease, this review synthesizes findings from only three controlled trials, meaning any conclusions carry substantial uncertainty. The abstract does not specify whether these were randomized or non-randomized controlled trials beyond noting they were clinical controlled trials.
The clearest signal was improvement in Dynamic Gait Index scores (SMD 1.47, 95% CI 0.62 to 2.32) with a PEDro score of 5/10, indicating moderate-level evidence. Secondary findings, significant improvements in stride length and limb/shoulder/hip movement velocities, came from a single trial scoring only 2/10 on PEDro, a limited level of evidence, while joint range of motion during gait showed no significant between-group difference in a trial scoring 6/10. This body of evidence is too small and heterogeneous in quality to support firm expectations about manual therapy's effect on gait, and the isolated positive findings in low-quality trials could reflect chance or bias rather than a true treatment effect.
The main limitation applicable here is the small number of included trials and inconsistent methodological quality across them.
A systematic review of only three controlled trials examined manual therapy's effect on gait in Parkinson's disease, so conclusions remain tentative.
Manual therapy was linked to improvement on the Dynamic Gait Index (standardized mean difference 1.47, 95% CI 0.62 to 2.32), rated as moderate-quality evidence from a PEDro score of 5/10.
Other gait measures such as stride length and arm/shoulder/hip movement velocity showed significant improvement in a single low-quality trial (PEDro 2/10), while joint range of motion during gait showed no significant between-group difference (PEDro 6/10).
Source
Sensors (Basel, Switzerland)
Delafontaine A, Vialleron T, Barbier G et al. · 2024
doi: 10.3390/s24020354