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Neurological Rehab Randomised controlled trial

The effect of a motor relearning on balance and postural control in patients after stroke: An open-label randomized controlled trial.

This randomized controlled trial asked whether task-specific training based on motor relearning principles (MRP) works better than conventional physical therapy (CPT) for improving balance in people recovering from stroke. Sixty-three subacute stroke patients were randomly assigned to MRP (n=32) or CPT (n=31), both delivered as 8 weeks of therapy, three sessions per week, one hour each. Balance was measured with the Berg Balance Scale and postural control with posturography (a device-based sway measurement), assessed before treatment, right after, and at 3-month follow-up. The MRP group showed significantly larger improvements than the CPT group on both measures immediately after treatment, and these gains were sustained at the 3-month follow-up.

The authors describe the effect sizes as large. However, the study was open-label, meaning participants and assessors knew which treatment was given, which can influence results and is the main limitation the authors themselves flag.

This study looked at two types of physical therapy for balance problems after stroke, a common issue that increases fall risk. Researchers compared a therapy approach called motor relearning training, which uses task-specific exercises, against standard conventional physical therapy.

63 people who had recently had a stroke took part, split into two groups, each doing 8 weeks of therapy (three one-hour sessions per week). People in the motor relearning group showed significantly bigger improvements in balance and postural control (measured by a standard balance test and a device that tracks body sway) compared to those receiving conventional therapy. These improvements were still present three months after treatment ended. The main caveat is that this was an open-label trial, meaning both patients and therapists knew which treatment was being given.

This kind of design can introduce bias, since expectations about a newer-sounding approach might influence how people perform on tests or how outcomes are rated. The findings are promising but would benefit from confirmation in trials where assessors are blinded.

This is a summary of research, not medical advice. Talk to your own healthcare provider about anything affecting your care.

This RCT compared task-specific training based on motor relearning principles against conventional physical therapy in 63 subacute stroke patients (MRP n=32, CPT n=31), with balance assessed via the Berg Balance Scale and posturographic Balance Index at baseline, post-intervention (8 weeks, 3x/week, 1 hour sessions), and 3-month follow-up. The MRP group showed statistically significant between-group differences favoring MRP on both outcomes, with large reported effect sizes (BBS d=2.98; Balance Index d=2.83), and these differences persisted at follow-up. The inclusion of posturographic assessment alongside a clinical scale is a methodological strength, offering objective biomechanical data alongside the more subjective clinical measure.

However, the open-label design is a substantial limitation: without blinding of assessors or participants, performance and rating bias cannot be excluded, particularly for a subjectively scored measure like the BBS. The abstract does not report on treatment fidelity, dropout rates, or adverse events, limiting further appraisal.

The authors themselves call for future trials with adequate blinding, and their conclusions should be read as encouraging within-trial signal rather than definitive evidence given this design constraint.

1

In 63 subacute stroke patients, task-specific motor relearning training produced statistically significantly larger improvements in Berg Balance Scale and posturographic Balance Index scores than conventional physical therapy after 8 weeks.

2

Between-group improvements favoring motor relearning training were sustained at 3-month follow-up on both balance measures.

3

The trial was open-label without blinding of participants or assessors, a design limitation that may bias subjectively scored outcomes and warrants replication with blinded assessment.

Source

European stroke journal

Ghrouz A, Guillen-Sola A, Morgado-Perez A et al. · 2024

doi: 10.1177/23969873231220218

Read paper →
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A note on accuracy

Summaries are AI-generated from each paper's abstract and are for learning, not clinical decision-making. They may miss nuance or occasionally misstate details from the source, so always read the original paper before applying findings in practice. Nothing on this site is medical advice.