Effectiveness of Physical Therapy Interventions in Children with Brachial Plexus Birth Injury: A Systematic Review.
Featured on Physle Daily · Tuesday, 28 July 2026
Researchers looked at seven randomized controlled trials to see how well physical therapy works for children born with brachial plexus injury, a nerve injury affecting the arm and shoulder. They measured how much the children could move their arms, how strong their muscles were, and the density of their bones. The studies involved infants and older children, though there were not many studies to choose from, which limited what they could conclude.
When physical therapy was combined with other treatments, the improvements in movement and strength appeared somewhat larger than with physical therapy alone, but the quality of the evidence behind these findings was low. Overall, the review suggests that physical therapy either on its own or alongside other treatments may help children with this injury in the shorter term, though much remains unclear about the best approach.
A team of researchers looked at studies about how physical therapy helps children who were born with a nerve injury affecting the arm and shoulder. They found that therapy does seem to help children improve how much they can move their arm and how strong their muscles become.
When children had physical therapy combined with other treatments, they appeared to improve somewhat more than those who only did physical therapy, though the studies were not always very detailed or high quality. The research focused on improvements that happened over a shorter period of time, so it is not yet clear how long these gains last or what happens over months and years.
There are still a lot of questions that doctors and therapists do not have clear answers to, which means your own child's therapy plan should be tailored to their specific needs.
This is a summary of research, not medical advice. Talk to your own healthcare provider about anything affecting your care.
This systematic review included only seven randomized controlled trials examining physical therapy for pediatric brachial plexus birth injury, which reflects how sparse the evidence base is in this area. The primary outcomes tracked were range of motion, muscle strength, and bone mineral density across infants and children.
The heterogeneity of interventions and participant characteristics meant pooling data was limited, but the largest effect sizes appeared when physical therapy was combined with other modalities, despite low GRADE quality of evidence. The abstract does not specify which combinations were most effective or detail the nature of the comparison interventions.
The review indicates that physical therapy shows short-term effectiveness but leaves unanswered questions about long-term outcomes, optimal timing, intensity, and whether certain combinations of treatment truly outperform others in rigorous head-to-head trials. Future research with more standardized protocols and longer follow-up periods would better clarify the role of physical therapy in this population.
Seven randomized controlled trials met inclusion criteria, comprising two studies in infants and five in children, from 932 screened titles and abstracts.
Combined physical therapy with other interventions showed larger effect sizes than physical therapy alone for range of motion, muscle strength, and bone mineral density, but the quality of evidence was rated as low.
Physical therapy interventions appear effective for short-term improvements in disability in children with brachial plexus birth injury, though long-term outcomes remain unclear.
Source
Developmental neurorehabilitation
de Matos MA, Souto DO, Soares BA et al. · 2023
doi: 10.1080/17518423.2022.2099995