Yoga, Physical Therapy and Home Exercise Effects on Chronic Low Back Pain: Pain Perception, Function, Stress, and Quality of Life in a Randomized Trial.
Featured on Physle Daily · Wednesday, 16 September 2026
Chronic low back pain is common, and clinicians have several exercise-based options, but it's often unclear whether one approach beats another. This trial compared three six-week programs: supervised physical therapy combining spinal stabilization exercises with heat and electrical stimulation, a home exercise version of the same stabilization exercises, and a yoga program, in a small group of adults with chronic low back pain. All three groups showed improvements over the six weeks in pain, function, pain sensitivity, central sensitization, anxiety, core muscle activation, and quality of life. The physical therapy group showed a somewhat larger improvement in function scores than the other two groups, and cortisol levels dropped only in that group.
Overall, no single approach stood out as clearly superior across most measures. Because the sample was small and there was no untreated comparison group, it's hard to know how much of the improvement reflects the specific treatments versus other factors like time or attention, so these findings should be read as preliminary.
If you live with chronic low back pain, you've probably wondered whether yoga, in-clinic physical therapy, or exercises done at home make the biggest difference. This study followed 54 people with chronic low back pain who were randomly assigned to one of these three six-week programs to compare their effects on pain, physical function, stress hormones, and quality of life. The encouraging part is that people in all three groups reported improvements in pain, function, muscle activation, anxiety, and quality of life.
The physical therapy group showed a bit more improvement in function than the other two, and this was the only group where a stress hormone called cortisol dropped afterward. However, this doesn't mean any one approach was clearly proven better than the others for most measures. The study was small and didn't include a group who received no treatment at all, so we can't be fully certain how much of the improvement came from the exercises themselves rather than other factors.
These results suggest multiple approaches may have a role, but larger studies are needed.
This is a summary of research, not medical advice. Talk to your own healthcare provider about anything affecting your care.
This randomized trial (n=54) compared three six-week interventions for chronic low back pain: physical therapy combining spinal stabilization exercises with local heat and transcutaneous electrical stimulation, a home-based version of the same stabilization exercises, and yoga. Primary outcomes were pain (Visual Analog Scale) and function (Oswestry Disability Index); secondary outcomes included kinesiophobia, central sensitization inventory, pressure pain thresholds, state anxiety, plasma cortisol and DHEA-S, transversus abdominis activation, and quality of life (Nottingham Health Profile). All three groups improved significantly (p<.05) on VAS, ODI, pain sensitivity, central sensitization, anxiety, TrA activation, and quality of life from pre- to post-intervention.
The physical therapy group showed a significantly greater improvement on ODI than the other groups, and it was the only group with a significant cortisol reduction; DHEA-S and the Nottingham Health Profile social isolation subscale showed no change in any group. As a within-group pre-post design across three active arms without an untreated control, the trial cannot isolate treatment-specific effects from natural improvement or attention effects, and the modest sample size limits precision and generalizability. The abstract indicates no intervention was uniformly superior, supporting individualized rather than hierarchical treatment selection.
All three six-week programs, physical therapy, home exercise, and yoga, produced statistically significant within-group improvements in pain, function, pain sensitivity, central sensitization, anxiety, and quality of life.
The physical therapy group showed a significantly greater improvement in function (Oswestry Disability Index) than the home exercise or yoga groups, and was the only group with a significant drop in cortisol.
With only 54 participants across three active treatment arms and no untreated control group, this trial cannot confirm that the exercises themselves, rather than time or attention, caused the observed improvements.
Source
Perceptual and motor skills
Oz M, Ulger O · 2024
doi: 10.1177/00315125241292235