Effectiveness of Cognitive Functional Therapy Versus Core Exercises and Manual Therapy in Patients With Chronic Low Back Pain After Spinal Surgery: Randomized Controlled Trial.
Featured on Physle Daily · Thursday, 8 October 2026
People who still have chronic low back pain after spinal surgery present a genuinely difficult treatment problem, and this trial asked whether a psychologically informed approach called cognitive functional therapy works better than a more conventional program combining core exercises and manual therapy. Eighty adults with persistent pain after spinal surgery were randomized to one of the two approaches, delivered weekly for up to 12 weeks, with pain intensity and patient-rated function as the main outcomes. The cognitive functional therapy group reported larger improvements in both pain and function immediately after treatment, and this advantage was still present around five months later. The effect sizes were described as large, which is notable in a population that is often hard to treat.
The main limitation is that this is a single trial of 80 participants (75 analyzed for primary outcomes) from two Brazilian sites, so while the result is encouraging, it has not yet been replicated elsewhere.
If you've had back surgery but still live with chronic low back pain, you know how frustrating it can be to find a treatment that actually helps. This study compared two physical therapy approaches for people in exactly that situation: one called cognitive functional therapy, which focuses on how a person thinks about and moves with their pain, and a more standard approach combining core strengthening exercises with hands-on manual therapy.
Eighty people took part, receiving weekly sessions over as long as 12 weeks. Those who received cognitive functional therapy reported bigger improvements in both pain levels and their ability to do meaningful daily activities, right after treatment and still around five months later. The differences between groups were fairly large by research standards.
That said, this is one trial conducted at two sites in Brazil, so while the findings are promising for this specific group of post-surgery patients, they would need to be confirmed by further research before being considered well established.
This is a summary of research, not medical advice. Talk to your own healthcare provider about anything affecting your care.
This trial speaks directly to a common clinical dilemma: what to offer patients whose low back pain persists after spinal surgery, when standard core-and-manual-therapy approaches often fall short. It compared cognitive functional therapy against a core exercise plus manual therapy program in 80 participants, with 75 (93.7%) contributing primary outcome data at the post-intervention timepoint around 10 weeks and again at 22-week follow-up. Cognitive functional therapy showed statistically significant and large between-group effects for both pain (mean difference 2.42, effect size d=0.85) and patient-specific function (mean difference -2.47, effect size 0.95), with the advantage retained though somewhat attenuated at 22 weeks.
This informs reasoning about treatment selection for the post-surgical chronic pain subgroup specifically, rather than chronic low back pain generally, and suggests the behavioral, pain-education components of cognitive functional therapy may offer something beyond exercise and manual technique alone in this population. What the trial does not establish is generalizability beyond two Brazilian sites and this specific post-surgical cohort, long-term durability beyond 22 weeks, or the relative contribution of therapist contact time and attention between arms, since treatment intensity and contact were not clearly equated in the abstract. Replication in other settings and surgical subtypes would be needed before drawing firm practice conclusions.
In this randomized trial of 80 adults with chronic low back pain after spinal surgery, cognitive functional therapy produced significantly greater reductions in pain intensity than core exercises plus manual therapy after treatment (mean difference 2.42, large effect size d=0.85).
Cognitive functional therapy also showed significantly greater improvement in patient-specific function compared with core exercises plus manual therapy (mean difference -2.47, effect size 0.95), with both the pain and function advantages still present though somewhat smaller at 22-week follow-up.
This was a single trial conducted at two sites in Brazil with 75 of 80 participants (93.7%) analyzed for primary outcomes, so the findings are promising but have not yet been replicated in other settings or surgical populations.
Source
Physical therapy
Avila L, da Silva MD, Neves ML et al. · 2024
doi: 10.1093/ptj/pzad105