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Sports & Athletic Rehab Systematic review and meta-analysis

Manual therapy and exercise for lateral elbow pain.

Lateral elbow pain, often called tennis elbow, is commonly treated with manual therapy (hands-on techniques like joint mobilisation or massage), prescribed exercises, or a combination of both. This review pooled findings from 23 randomised trials involving 1612 adults to ask whether these treatments actually help compared with placebo or with minimal or no treatment at all. The results were modest. One small placebo-controlled trial hinted that manual therapy might ease pain and disability over a few weeks, but this came from a single study with no long-term follow-up.

Across a larger set of trials comparing these treatments to minimal intervention, pain and disability improved only slightly at four weeks to three months, and these small gains faded over time, with little to no improvement in quality of life or treatment success reported by participants. The main limitation is that most trials could not blind participants to which treatment they received, raising the risk of expectation effects, and the certainty of evidence throughout was rated low.

If you have lateral elbow pain, sometimes called tennis elbow, you may have been offered hands-on treatment from a physiotherapist, exercises to do at home, or both. This review looked at 23 studies with over 1600 adults to see how well these approaches actually work. The findings were mixed and modest.

One small study found that hands-on treatment might reduce pain and disability more than a fake (placebo) version of the same treatment over a few weeks, but this result comes from just one small trial, so it is not a strong conclusion. When manual therapy and exercise were compared to doing very little or nothing, people did see a slight improvement in pain and disability after a few weeks to months, but this improvement was small and did not last, and people did not report meaningfully better quality of life or overall treatment success.

Because most people in these studies knew which treatment they were getting, their expectations may have influenced how they rated their symptoms, which makes the results less certain.

This is a summary of research, not medical advice. Talk to your own healthcare provider about anything affecting your care.

For clinicians weighing whether manual therapy and prescribed exercise meaningfully change outcomes in lateral elbow pain, this Cochrane review offers a cautious answer. It pooled 23 randomised or quasi-randomised trials (1612 participants) across several comparisons: manual therapy versus placebo manual therapy (one trial, 23 participants), manual therapy, exercise or both versus minimal or no intervention (12 trials, 1124 participants), manual therapy plus exercise versus exercise alone (six trials, 228 participants), and combinations with glucocorticoid injection (five trials, 237 participants). The single placebo-controlled trial suggested a possible benefit of manual therapy on pain (mean difference -2.1 points on a 0-10 scale) and disability (mean difference -25 points on a 0-100 scale) at two to three weeks, though the confidence intervals were wide and no follow-up existed beyond treatment end.

Against minimal intervention, pooled data across 10 to 12 trials showed only small reductions in pain (-0.53 points) and disability (-5.00 points) at four weeks to three months, with little to no improvement in quality of life or participant-reported treatment success, and these benefits were not sustained. This informs expectations about effect size and durability rather than confirming clinical usefulness: 21 of 23 trials lacked blinding, introducing performance and detection bias, and indirectness from multimodal interventions further limits interpretation. Adverse events, described as mild and transient with no serious events reported, were more frequent in treated groups, though event counts were too small for certainty.

1

Low-certainty evidence from a single small trial (23 participants) suggests manual therapy may reduce pain and disability more than placebo manual therapy at two to three weeks, but longer-term effects are unknown.

2

Across 12 trials (1023 participants for pain), manual therapy, prescribed exercises or both produced only a slight reduction in pain and disability compared with minimal or no intervention at four weeks to three months, and these small effects were not sustained.

3

The evidence base has important limitations, including lack of blinding in 21 of 23 trials and risks of selection, attrition and selective reporting bias, which lowers confidence in the findings.

Source

The Cochrane database of systematic reviews

Wallis JA, Bourne AM, Jessup RL et al. · 2024

doi: 10.1002/14651858.CD013042.pub2

Read paper →
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A note on accuracy

Summaries are AI-generated from each paper's abstract and are for learning, not clinical decision-making. They may miss nuance or occasionally misstate details from the source, so always read the original paper before applying findings in practice. Nothing on this site is medical advice.