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Manual Therapy Randomised controlled trial

A Single-Center Study Comparing the Effects of Thoracic Spine Manipulation vs Mobility Exercises in 26 Office Workers with Chronic Neck Pain: A Randomized Controlled Clinical Study.

This small randomized controlled trial from a single center compared two approaches to treating chronic neck pain (lasting more than 12 weeks) in 26 office workers. Both groups received the same base treatment (cervical joint mobilization and deep neck flexor exercises), and one group additionally did thoracic spine mobility exercises (TSME, n=13) while the other received thoracic spine manipulation (TSM, n=13), over 6 weeks. Both groups showed significant improvements in neck and thoracic spine range of motion, pain ratings, and disability scores after treatment compared to before. When the two groups were compared directly, only two specific neck movements (right lateral flexion and right rotation) differed significantly between them; other measures of range of motion, pain, and disability showed no significant difference.

With only 26 participants split across two groups, this study is too small to draw firm conclusions about which approach works better, and both treatments included a shared base intervention that likely contributed to the improvements seen.

This study looked at 26 office workers with long-lasting neck pain, comparing two add-on treatments alongside standard neck exercises and joint mobilization: thoracic spine (upper back) mobility exercises versus thoracic spine manipulation done by a practitioner. Researchers wanted to know which approach worked better for improving neck movement, pain, and disability. Both groups improved in neck and upper back movement, pain levels, and disability scores over the 6-week study.

However, when comparing the two groups directly, there was little difference between them, except for two specific neck movements. This suggests that both approaches may have offered similar benefits, though the study cannot say for certain that either treatment specifically caused the improvements, since both groups also received the same base treatment. With only 13 people in each group, this is a small study, and the findings should be seen as preliminary rather than conclusive.

No safety information was reported in the abstract.

This is a summary of research, not medical advice. Talk to your own healthcare provider about anything affecting your care.

This RCT compared thoracic spine mobility exercise (TSME) versus thoracic spine manipulation (TSM) as adjuncts to a shared base intervention (cervical joint mobilization plus deep cervical flexor exercises) in 26 office workers with chronic non-specific neck pain (>12 weeks duration), over a 6-week program. Both groups demonstrated statistically significant within-group improvements in cervical and thoracic ROM, NPRS, and NDI. Between-group comparisons found statistically significant differences only for cervical right lateral flexion and right rotation, with no significant between-group differences in thoracic ROM, pain, or disability.

This pattern suggests comparable effectiveness between TSME and TSM as adjuncts, though the shared base treatment limits causal attribution of improvements to either add-on intervention specifically. The primary limitation is the very small sample (n=13 per arm), which constrains statistical power and generalizability. Single-center design and lack of reported blinding details further limit certainty.

No long-term follow-up or adverse event data were mentioned in the abstract. These findings should be considered preliminary given the sample size.

1

In 26 office workers with chronic neck pain, thoracic spine mobility exercises and thoracic spine manipulation both produced significant within-group improvements in neck and thoracic ROM, pain, and disability after 6 weeks.

2

Between-group comparisons found statistically significant differences only in cervical right lateral flexion and right rotation, with no significant differences in thoracic ROM, pain, or disability scores.

3

With only 13 participants per group, this small single-center trial limits confidence in the findings and generalizability to broader populations.

Source

Medical science monitor : international medical journal of experimental and clinical research

Seo J, Song C, Shin D · 2022

doi: 10.12659/MSM.937316

Read paper →
Previously in Manual Therapy
2026-08-07Which Portion of Physiotherapy Treatments' Effect Is Not Attributable to the Specific Effects in People With Musculoskeletal Pain? A Meta-Analysis of Randomized Placebo-Controlled Trials.2026-08-06The Clinical Significance of Mulligan's Mobilization with Movement in Shoulder Pathologies: A Systematic Review and Meta-Analysis.2026-08-05The combined effects of manual therapy and exercise on pain and related disability for individuals with nonspecific neck pain: A systematic review with meta-analysis. Browse the full Manual Therapy archive →
A note on accuracy

Summaries are AI-generated from each paper's abstract and are for learning, not clinical decision-making. They may miss nuance or occasionally misstate details from the source, so always read the original paper before applying findings in practice. Nothing on this site is medical advice.