Effectiveness of Myofascial Release Compared to Manual Lymphatic Drainage in Reducing Post-Treatment Shoulder Pain and Stiffness Among Patients Who Underwent Breast Cancer Surgery and Adjuvant Radiotherapy: Randomised controlled trial.
Featured on Physle Daily · Monday, 5 October 2026
Shoulder pain and stiffness are common after breast cancer surgery and radiotherapy, and physiotherapists use various hands-on techniques to try to ease them, though which approach works best isn't settled. This trial compared myofascial release, a form of massage aimed at loosening restricted tissue, with manual lymphatic drainage, a gentler massage technique often used to manage swelling, in 98 patients with shoulder complications after breast cancer treatment. Outcomes were measured at the start, after four sessions, and one month later. The myofascial release group showed greater reductions in pain and shoulder dysfunction, better improvement in shoulder range of movement, and better quality of life scores compared to the manual lymphatic drainage group, with differences reported as statistically significant.
This is an interesting signal that the choice of manual technique may matter for this patient group, but the abstract does not describe blinding, dropout numbers, or longer-term follow-up, so how durable or generalisable these benefits are remains unclear.
If you've had breast cancer surgery followed by radiotherapy, shoulder pain and stiffness afterward are a common and frustrating problem. This study looked at two different hands-on massage-based treatments physiotherapists sometimes use to help with that, one called myofascial release and another called manual lymphatic drainage, to see which helped more. Researchers followed 98 patients, checking their pain, shoulder movement, shoulder function, and quality of life at the start, after four treatment sessions, and again a month later.
People who received myofascial release showed bigger improvements across all these measures compared to those who received manual lymphatic drainage, and the difference was statistically meaningful, not just a chance pattern. This is encouraging information, but it comes from one study, and the abstract doesn't say how many people dropped out, whether assessors knew which treatment each patient received, or how people fared beyond the one month follow-up. So while the findings point in a clear direction, they shouldn't be read as the final word on which treatment is best for everyone in this situation.
This is a summary of research, not medical advice. Talk to your own healthcare provider about anything affecting your care.
For physiotherapists treating shoulder pain and stiffness following breast cancer surgery and adjuvant radiotherapy, a recurring clinical question is which manual therapy approach offers meaningful functional benefit, given how often lymphatic drainage is used by default for this population. This randomised trial directly compares myofascial release against manual lymphatic drainage in 98 patients, assessing pain, shoulder range of movement, dysfunction, and quality of life at baseline, after four sessions, and one month post-treatment. The myofascial release group showed statistically significant improvements across all four outcomes compared with manual lymphatic drainage, including quality of life, where the drainage group's change did not reach significance.
This raises the possibility that myofascial techniques may offer additional functional benefit in this setting, though the abstract does not report blinding of assessors, adverse events, or whether assessors were independent of the treating physiotherapist, all of which affect confidence in the magnitude of difference observed. The trial does not establish long-term durability beyond one month, nor does it clarify dropout or analysed-versus-enrolled numbers beyond the total of 98, which limits certainty about how representative the reported improvements are of the full enrolled group.
In this randomised trial of 98 patients with post-treatment shoulder complications after breast cancer surgery, myofascial release produced statistically significant improvements in pain, shoulder range of movement, and shoulder dysfunction compared with manual lymphatic drainage.
Quality of life scores improved significantly in the myofascial release group, while the manual lymphatic drainage group's change did not reach statistical significance.
The abstract does not report blinding, adverse events, or dropout details, and follow-up extended only to one month, limiting confidence in the durability and generalisability of the results.
Source
Sultan Qaboos University medical journal
Vijayakumar C, Jain A, Kalaranjani M et al. · 2025
doi: 10.18295/2075-0528.2841