Running is acceptable and efficacious in adults with non-specific chronic low back pain: the ASTEROID randomised controlled trial.
Featured on Physle Daily · Wednesday, 7 October 2026
People with chronic low back pain are often told to be cautious with high-impact activities like running, but whether a structured running programme could actually help them has not been well studied. This Australian trial randomised 40 adults aged 18 to 45 with non-specific chronic low back pain to either a 12-week progressive run-walk programme, delivered digitally and supported remotely by an exercise physiologist, or a waitlist control group who received no intervention during that period. After 12 weeks, participants following the run-walk programme reported lower average and current pain intensity and less disability than those on the waitlist, with no one dropping out and average adherence around 70% of planned sessions. Nine mild, study-related adverse events occurred, mostly lower limb injuries.
The main limitation is the trial's small size and narrow age range, and because the control group received no attention or support, part of the benefit may reflect that extra contact rather than running itself.
If you live with ongoing low back pain, you may have been warned away from running, but this small study asked whether a carefully structured running programme could actually help rather than harm. Forty adults aged 18 to 45 with long-term, non-specific low back pain were split into two groups: one followed a 12-week programme alternating running and walking, done three times a week with remote support from an exercise physiologist, while the other group waited and received no programme. By the end of 12 weeks, people doing the run-walk programme reported less pain and less disability than those who waited, and nobody dropped out of the study.
Most people stuck with about seven out of ten planned sessions, and while a few mild injuries or pain flare-ups occurred, these were manageable. Because this was a small trial of younger and middle-aged adults, and because the comparison group got no extra attention or encouragement, some of the improvement may reflect that support rather than running alone.
It's a promising early signal, not a final answer.
This is a summary of research, not medical advice. Talk to your own healthcare provider about anything affecting your care.
This trial speaks to a common clinical uncertainty: whether running is a viable form of exercise, rather than a risk to be avoided, for adults with chronic non-specific low back pain. In this randomised controlled trial, 40 participants aged 18 to 45 were allocated to a 12-week progressive run-walk interval programme (three 30-minute sessions weekly, remotely supported by an exercise physiologist) or a waitlist control with no intervention. At 12 weeks, the intervention group showed statistically significant between-group improvements in average pain intensity (-15.30 points, 95% CI -25.33 to -5.27), current pain intensity (-19.35 points, 95% CI -32.01 to -6.69) and disability (-5.20 points, 95% CI -10.12 to -0.24) on standard measures.
There was no attrition and adherence averaged 70%; nine non-serious adverse events judged likely related to the programme were reported, mainly lower limb injury or pain. Because the control group received no contact or support, part of the observed benefit may reflect attention or expectation rather than running per se, and the small, age-restricted sample limits generalisability.
This does not establish long-term outcomes, optimal dosing, or suitability for older or more complex presentations of chronic low back pain.
In this small trial of 40 adults aged 18-45, a 12-week run-walk programme produced statistically significant improvements in pain intensity and disability compared with a no-treatment waitlist group.
No participants dropped out and average training adherence was 70% of planned sessions, suggesting the programme was acceptable to this specific population, though the sample was small.
Nine non-serious adverse events judged likely related to the programme were reported, mostly lower limb injury or pain, alongside one case of fainting linked to an underlying condition and one instance of low back pain.
Source
British journal of sports medicine
Neason C, Samanna CL, Tagliaferri SD et al. · 2025
doi: 10.1136/bjsports-2024-108245