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Chronic Pain Systematic review

Chronic pain: are there effective therapeutic exercises in rehabilitation treatment? A narrative review.

Chronic pain remains a puzzle for both patients and clinicians. Even though we understand more about how chronic pain develops in the body, and we have many medications to treat it, plenty of people still don't get the relief they need from drugs alone. This narrative review looked at recent research from the past five years to see whether rehabilitation exercises actually help.

The researchers examined nineteen relevant papers, covering both standard chronic pain conditions and a specific type called nociplastic pain, which involves altered pain processing in the nervous system. What they found was honest and somewhat sobering: no single treatment stood out as clearly better than the others. Instead, the evidence suggests that combining several different approaches tends to work better than relying on just one thing.

Chronic pain is complex, and if you've felt frustrated that pain medication alone hasn't solved your problem, you're not alone. Researchers looked at what rehabilitation and exercise approaches have actually been tested to help with long-term pain.

What they found was that there isn't one magic solution that works best for everyone, but rather that mixing different treatments together seems to give better results than doing one thing by itself. The review also highlighted that we still need more research to understand exactly which types of exercises help the most, especially exercises that involve balance, coordination, and body awareness. Right now, there's room for improvement in how we understand and approach chronic pain treatment, and more studies are underway to clarify what works.

This is a summary of research, not medical advice. Talk to your own healthcare provider about anything affecting your care.

This narrative review reflects a familiar clinical reality: the chronic pain literature is large but surprisingly non-directive when it comes to exercise specificity. The authors screened recent randomised controlled trials and systematic reviews over a five-year window and found that while rehabilitation approaches show potential, no single intervention emerged as clearly superior.

This absence of a winner is itself meaningful and suggests that the heterogeneity of chronic pain populations may demand individualised or multimodal approaches. One notable gap the authors identified is the lack of well-designed studies isolating proprioceptive elements within exercise programs. Currently, we have evidence that exercise combinations work, but less clarity on which mechanistic elements drive those effects.

The implication is that while rehabilitation remains part of the treatment landscape, the evidence for which specific exercise prescriptions best serve which presentations remains incomplete.

1

No single rehabilitative treatment was found to be more effective than another; combined approaches appeared to yield better outcomes.

2

Thirteen papers on chronic pain and six papers on nociplastic pain were included in the analysis of recent literature.

3

Future research should focus on exercises with clear proprioceptive components to better understand their role in chronic pain management.

Source

La Clinica terapeutica

Camerota F, Petronelli G, Savina A et al. · 2024

doi: 10.7417/CT.2024.5139

Read paper →
Previously in Chronic Pain
2026-07-20Exercise-induced changes in central sensitization outcomes in individuals with chronic musculoskeletal pain: A systematic review with meta-analysis.2026-07-19Pain Science Education, Stress Management, and Cognition-Targeted Exercise Therapy in Chronic Whiplash Disorders: A Randomized Clinical Trial.2026-07-18The most effective therapeutic exercises for pain intensity in women with fibromyalgia: A systematic review and network meta-analysis. Browse the full Chronic Pain archive →
A note on accuracy

Summaries are AI-generated from each paper's abstract and are for learning, not clinical decision-making. They may miss nuance or occasionally misstate details from the source, so always read the original paper before applying findings in practice. Nothing on this site is medical advice.