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Running & Endurance Randomised controlled trial

The content of diagnostic information has an immediate effect on pain with loading in people with midportion Achilles tendinopathy: a randomized clinical experiment.

How a clinician explains the cause of pain might sound like a small detail, but contemporary pain models suggest a patient's beliefs about what is going wrong could shape how much pain they actually feel. This trial tested that idea directly in recreational runners with Achilles tendinopathy, a persistent tendon pain condition. Fifty participants were randomised to hear one of two explanations before a standardised hopping task: one framed the pain as being driven by changes in muscle function, the other emphasised tendon tissue damage.

The group given the muscle-function explanation reported lower pain intensity during hopping immediately afterward compared to the tendon-pathology group. This is an interesting finding because it suggests the words used to explain pain can have a measurable, immediate effect on pain during loading, separate from any physical treatment. The effect on lower limb stiffness during hopping was uncertain, and there was no difference in how long it took pain to settle after the task. The main limitation is that this was a single small experiment measuring an immediate effect, not long-term outcomes.

If you've had Achilles tendon pain from running, you may have wondered whether how a clinician explains your pain actually matters, beyond just getting treatment. This study looked at exactly that question in fifty recreational runners with Achilles tendinopathy.

Everyone did the same hopping test, but before it, one group was told their pain was mainly related to changes in how their muscles were working, while the other group was told it was mainly related to damage in the tendon tissue itself. People who received the muscle-function explanation reported less pain during the hopping test than those told about tendon damage. There was no clear difference between groups in how quickly pain eased afterward, and the effect on how their leg responded to impact (a measure called lower limb stiffness) was uncertain.

This suggests the way pain is explained could influence how much pain someone feels in the moment, though this comes from one small study measuring an immediate effect, not from testing whether it changes recovery over time.

This is a summary of research, not medical advice. Talk to your own healthcare provider about anything affecting your care.

This randomised clinical experiment enrolled 50 recreational runners with midportion Achilles tendinopathy and compared two verbal explanations of pain: an experimental framing emphasising altered muscle function versus a control framing emphasising tendon pathology, prior to a standardised hopping task. The primary outcome, maximal pain intensity during hopping on a 0-100mm visual analogue scale, was lower in the experimental group post-intervention (mean difference 12.3mm, 95% CI 3.2 to 21.5), a statistically significant between-group difference given the interval excludes zero. Secondary outcomes were less conclusive.

Lower limb stiffness while hopping was higher in the experimental group but the estimate was imprecise (mean difference -1546 Nm-1, 95% CI -3296 to 204), crossing zero, so this effect remains uncertain. Time-to-ease showed no difference between groups (mean difference 0s, 95% CI -11 to 11), indicating no signal of benefit on this measure. The design supports a causal interpretation of diagnostic framing on immediate pain during loading, consistent with contemporary pain models, but the sample is small and the outcome reflects an acute effect during a single testing session rather than functional recovery or longer-term pain trajectories.

No adverse events were reported in the abstract. Replication in larger samples and assessment of downstream clinical outcomes would be needed before drawing broader practice implications.

1

In this small randomised experiment of 50 runners with Achilles tendinopathy, those given an explanation emphasising muscle function reported significantly less pain during hopping than those given a tendon-pathology explanation (mean difference 12.3mm, 95% CI 3.2 to 21.5).

2

The effect of diagnostic framing on lower limb stiffness during hopping was uncertain, as the confidence interval for this secondary outcome crossed zero.

3

There was no detected difference between groups in how long it took pain to ease after the hopping task, with a mean difference of 0 seconds and a wide confidence interval spanning -11 to 11 seconds.

Source

Brazilian journal of physical therapy

Travers NJ, Travers MJ, Gibson W et al. · 2025

doi: 10.1016/j.bjpt.2025.101244

Read paper →
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A note on accuracy

Summaries are AI-generated from each paper's abstract and are for learning, not clinical decision-making. They may miss nuance or occasionally misstate details from the source, so always read the original paper before applying findings in practice. Nothing on this site is medical advice.